![]() Clinically, RA patients show painful swelling of the joints, joint deformity, and at later stage damage to a wide variety of body systems, including organs such as the heart and lungs ( 2). As an autoimmune and inflammatory disease, rheumatoid arthritis (RA) is characterized by persistent synovitis and systemic inflammation that is induced by the attack of the misguided immune system on healthy cells ( 1).
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